Bristol-Myers Squibb and Innate Pharma Announce Breakthrough Global License
Agreement for an Investigational Immuno-Oncology Biologic
(PRINCETON, New Jersey, and MARSEILLE, France, July 6, 2011) – Bristol-
Myers Squibb Company (NYSE: BMY) and Innate Pharma S.A. (Euronext Paris:
FR0010331421, IPH) today announced a global agreement for the development and commercialization of IPH2102, a novel antibody in Phase I development for the treatment of cancer.
Under the terms of the agreement, Innate Pharma will grant to Bristol-Myers
Squibb exclusive worldwide rights to develop, manufacture and commercialize IPH2102 and related compounds blocking KIR receptors. The agreement covers all potential indications for IPH2102. Innate Pharma will continue to develop IPH2102 in acute myeloid leukemia (AML) through to the end of Phase II. Innate Pharma will also provide pre-clinical support for the development of IPH2102. Bristol-Myers Squibb will fund the development of IPH2102, make an upfront payment of $35 million and additional payments of up to $430 million, depending on the achievement of pre-specified milestones during the development and commercialization period, as well as pre- specified tiered double-digit royalty payments on worldwide net sales.
« Bristol-Myers Squibb is dedicated to helping patients prevail over cancer, » said
Francis Cuss, senior vice president, Research, Bristol-Myers Squibb. « To help us in this mission, we are very pleased to join forces with Innate Pharma which has developed a deep understanding of the immune system. Working together we have the opportunity to develop IPH2102, a potential first-in-class biologic that may be able to harness a patient’s immune system in the fight against cancer. » 1/4

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